Nicole Leighton, CRNP

Nicole Leighton, CRNP, is a Psychiatric-Mental Health Nurse Practitioner with 16 years of combined experience in nursing and advanced psychiatric care. She serves as Director of Substance Use Disorder Treatment at Fine Tune Psychiatry and brings a specialized focus on addiction, women’s mental health, and perinatal care.

Specialties & Focus Areas

• Substance use disorders
• Alcohol usage disorder
• Opioid use disorder and harm reduction
• Women’s mental health
• Perinatal and maternal mental health
• LGBTQIA+ affirming care
• Co-occurring psychiatric conditions
• Medication Assisted Treatment
• Outpatient Alcohol Management

Who They Help

Nicole works with adults and has a focus on women’s mental health care, including pregnant and parenting women, as well as individuals navigating substance use and recovery, and patients seeking inclusive, gender affirming mental health care.

Treatment Approach

Nicole takes a holistic, patient-centered approach that integrates psychiatric care with substance use treatment. Her work emphasizes harm reduction, long-term recovery support, and individualized care planning, particularly during critical life stages such as pregnancy, parenthood and menopause.

Professional Background

Nicole is the Director of Substance Use Treatment Services at Fine Tune Psychiatry and former Lead Nurse Practitioner at Thomas Jefferson University Maternal Addictions Treatment Education and Research (MATER) Program. In this role, she specialized in treating substance use and psychiatric conditions in pregnant and parenting women.

She also serves as Clinical Adjunct Faculty at Thomas Jefferson University College of Nursing, where she teaches and mentors psychiatric nurse practitioner students. Additionally, she has contributed to the Thomas Jefferson University Hospital Addiction Medicine Fellowship, training healthcare professionals in opioid use disorder treatment and harm reduction strategies.

Certifications & Affiliations

• Psychiatric-Mental Health Nurse Practitioner (PMHNP-BC)
• Clinical Adjunct Faculty, Thomas Jefferson University
• Addiction Medicine Fellowship Contributor, Thomas Jefferson University Hospital

Locations & Availability

Nicole sees patients in Philadelphia, PA, and offers virtual care based on provider availability. Telehealth services may be available across Pennsylvania and New Jersey, depending on licensure.